Hazen,R.M.(2006): Mineral surfaces band the prebiotic selection and organization of biomolecules. American Mineralogist, 91, 1715-1729.

『鉱物表面およびその前生物的(プレバイオティック)淘汰と生体分子の組織化』


Abstract
 One of the most enigmatic steps in Earth's ancient transition from a lifeless planet to living world was the process or processes by which prebiotic organic molecules were selected, concentrated, and organized into the essential macromolecules of life. More than a half-century of theory and experiment points to the critical roles of mineral surfaces in the assembly of proteins, lipid bilayers, and genetic polymers. This review considers three aspects of this problems: (1) the self-assembly of lipids, which may be enhanced in the presence of minerals; (2) the role of minerals in polymerization of amino acids and nucleic acids; and (3) the selective adsorption of organic species, including chiral molecules, onto mineral surfaces.

Keywords: Surface studies; calcite; quartz; feldspar; new technique; microarray; origin of life』

Introduction
The emergence of life
Molecular self-organization
Mineral-induced polymerization
Molecular selection on mineral surfaces
 Differential molecular adsorption
 Origins of biochemical homochirality
 Theoretical modeling of mineral-molecule chiral interactions
 The real world
 A problem of combinatorics
Concluding remarks
Acknowledgments
References cited


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