『Abstract
One of the most enigmatic steps in Earth's ancient transition
from a lifeless planet to living world was the process or processes
by which prebiotic organic molecules were selected, concentrated,
and organized into the essential macromolecules of life. More
than a half-century of theory and experiment points to the critical
roles of mineral surfaces in the assembly of proteins, lipid bilayers,
and genetic polymers. This review considers three aspects of this
problems: (1) the self-assembly of lipids, which may be enhanced
in the presence of minerals; (2) the role of minerals in polymerization
of amino acids and nucleic acids; and (3) the selective adsorption
of organic species, including chiral molecules, onto mineral surfaces.
Keywords: Surface studies; calcite; quartz; feldspar; new technique;
microarray; origin of life』
Introduction
The emergence of life
Molecular self-organization
Mineral-induced polymerization
Molecular selection on mineral surfaces
Differential molecular adsorption
Origins of biochemical homochirality
Theoretical modeling of mineral-molecule chiral interactions
The real world
A problem of combinatorics
Concluding remarks
Acknowledgments
References cited